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ISSN: 0975-8585 January - February 2014 RJPBCS 5(1) Page No. 154 Research Journal of Pharmaceutical, Biological and Chemical Sciences In-vitro Experimental Studies on Selected Natural Gums and Resins for Their Antimicrobial Activity. Sravani P*, Y Kiranmayee, S Narasimha M, VS Reddy, S Asha and R Bharath Kumar. School of Biotechnology, Vignan University, Vadlamudi, Guntur-522213 Andhra Pradesh, India. ABSTRACT The present work will focus on the importance of plant base gums & resins and their antifungal and antibacterial activity. The plants were selected for Extracts to test their broad spectrum of anti microbial activity resistance against for the selected plant gums & resins as per the literature sources [1,2].There are about 7 indigenous gum/ resin yielding plants were selected which are having diversified uses like medicinal, economic, timber, fibre, gum and resin yielding plants like Acacia nilotica (from bark), Azadirachta indica (from bark), Bombax ceiba (from bark), Boswellia serrata (from bark), Cocos nucifera (from fruit),Mangifera indica (from fruit) & Prunus dulcis (from bark) etc.viz.of Guntur region (Vadlamudi, Tenali etc.), [3,4]. The Antifungal activity and the anti bacterial activity were tested against 7 plant gums and resins. A total number of 88 plant extracts (gums/resins) were prepared as an individual of 28 ethanol, methanol, acetone and hot water extracts belongs to the 7 individual plant species and another set of 6 plant extracts were prepared in combination of ethanol, methanol, acetone & n-butanol. 6 Plant extracts were prepared in multiple combinations ethanol , methanol, acetone, n-butanol. All these plant extracts were subjected against their antibacterial and anti fungal screening analysis, out of these plant extracts ( individual, combination & multiple) 5 plant extracts have been expressed the cognizable zone of expression i.e. 25 mm > 30 mm inhibition. Therefore these combinations were suggested for further analysis of gums &resins for their antimicrobial activity Keywords: In-vitro studies, selected plant gums & resins, antimicrobial activity. *Corresponding author