188宝金博页面版

·162·[36][37][38][39][40]gainst liver cancer[J]．0nc01 Lett，2018，15(5)：7014—7020．zHANGKQ，zHANG JRJNFYKDxx B．Therapeutic e归[ects of cr)Ⅺa—blation，瑚diorequenoy ablation，and microwave coagulation againstVX2 liver callcem comparative 8tudy in rabbit8[J]Joumal ofsou山em Medical universily，2007，27(9)：1431—1434．DUAN X，WANG M，HAN X，et a1．Combined use of microwaveablation and cell immunothe珀py induces nonspec击c immunity ofhepatocellular carcinoma model mice[J]．cell cycle，2020，19(24)：3595—3607．WEI Z，YANG X，YE X，et a1．Camrelizumab combined with mi—crowave ablation impmves the objective response rate in advancednon—small cell lung cancer[J]．J cancer Res‘rher，2019，15(7)：1629—1634．LEMDANI K，MIGNET N，BOUDY V，et a1．Local immunomodu—lation combined to mdiof诧quenoy ablation results in a completecure of local and distant colorectal carcinoma『J]．Oncoimmunolo—gy，2019，8(3)：1550342．KOELZER VH，LUGU A，DAWSON H，et a1．CD8／CD45R0 T—ceU infiltmtion in endoscopic biopsies 0fcolorectal cancer predictsnodal metastasis and suⅣival[J]．Tmnsl Med，2014，12(1)：81．[41][42][43][44][45][46]SELBY MJ，ENGELHARDT JJ，QUIGLEY M，et aL Anti—CTLA一4antibodies of Ig(泛a isotype enhance antitulnor activity through阳一duction of int眦umoml regulatory T cells[J]．Cancer ImmunologyResearch，2013，1(1)：32—42．DUFFY AG，ULAHANNAN SV，MAKOROVA—RUSHER O，eta1．7Ikmelimumab in combination wi山ablation in patients withadvanced hepatocellular ca∽inoma[J]．J Hepatol，2017，66(3)：545—551．KUD0 MJ0．Immuno—oncolog)r in hepatocellular carcinom8：2017 update[J]．0ncology，2017，93(1)：147．RAUFI A，TIRONA M‘rJCMR．Prospect of the use of checkpointinhibitors in hepatocellular cancer treatments[J]．callcer MallagRes，2017，9(9)：19—27．UU H，SHEN J，LU KJB，et a1．IL一6 and PD—L1 blockade com—bination inhibits hepatocellular ca地inoma cancer development inmousemodel[J]．Biochem BiophysRes commun，2017，486(2)：239—244．WANG Q，WU xJII_Primary aIld acquired resistance to PD一1／PD—L1 blockade in cancer treatment[J]．Int IIIlInunopha瑚acol，2017，46：210—219． (编校：张黛妮)预感性悲伤在晚期癌症患者中的研究进展陈海霞1，裴菊红1，南锐伶2，苟 玲1，张亚斌1，阎立新3，豆欣蔓2ReSearCh progreSS 0f antiCipafory grief in adVanCed CanCer patientSCHEN Haixial，PEI Juhon91，NAN Ruilin92，GOU Lin91，ZHANG Yabinl，YAN Lixin3，DOU Xinman21sc^ooZ矿№瑙i愕，如，砒o“‰而梆渺，G。邢M如船^oM 730000，吼iM；2Deponmem旷Ⅳu瑙i增；5Deponmem o，讹凡删mo砒，k，如ou踟劫em毋Jsecond舶印沈Z，能邶“k，如oH 730030，劬ino．【Abstract】7rhe incidence of cancer is high，a11d the trend of increasing year by year，w11ich is the leading cause ofdeath for patients．In recent years，the social and psychological pmblems of cancer patients have increasin出y attractedthe attention of the oncology community．Anticipatory grief is one of the most common morbid psychological reactionsin patients with advanced cancer，which seriously甜kcts the patient§treatment compliance，treatment efkct andquali—ty of life．This article focuses on the definition，assessment tools，innuencing factors，and intervention measures of pre—dictive sadness，with a view to providing a I℃f奄rence fbr clinical medical staff to psychologically intenrene in advancedcancer patients with anticipatoIy grief．【Key、^mrds】anticipatoIy目jef，cancer，advanced patientModem 0ncology 2022，30(01)：0162—0166【指示-陛摘要】癌症的发病率呈逐年上升的趋势，其并发症是导致患者死亡的主要原因。近年来，癌症患者的社会心理问题日益引起肿瘤学界的关注。预感性悲伤是晚期癌症患者中常见的病态心理反应之一，严重影【收稿日期】【基金项目】【作者单位】【作者简介】【通讯作者】2020一06—24【修回日期】2020—10一21中共甘肃省委组织部陇原青年创新创业人才项目(编号：2018—7)；兰州大学第二医院『f缶床拔尖技术研究项目(编号：cY2018一BJ20)；甘肃省兰州市城关区科技创新项目(编号：2019sHFz0019)1兰州大学护理学院，甘肃兰州7300002兰州大学第二医院护理部；3心理卫生科，甘肃兰州730030陈海霞(1988一)，女，甘肃兰州人，主管护师，硕士研究生在读，主要从事肿瘤专科护理研究。E—mail：872067560@qq．com豆欣蔓(1979一)，女，甘肃兰州人，主任护师，硕士生导师，主要从事护理管理、外科护理、循证护理研究。E—mail：douxm@lzu．edu cn万方数据