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    188宝金博页面版: Antibacterial and Phytochemical Evaluation of Three Medicinal…

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    内容提示： Akharaiyi F.C. and Boboye Bolatito, /Journal of Natural Products, Vol. 3(2010):27-34 Copyright ? 2009, Journal of Natural Products, INDIA, Dr. Sudhanshu Tiwari, All rights reserved 27 ISSN 0974 – 5211 Antibacterial and Phytochemical Evaluation of Three Medicinal Plants Akharaiyi Fred Coolborn* and Boboye Bolatito Microbiology Department, Federal University of Technology, P.M.B. 704, Akure, Ondo State, Nigeria * Corresponding author (Received 29 May 2009; Revised 04 June-11 July 2009; Acce...

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    Akharaiyi F.C. and Boboye Bolatito, /Journal of Natural Products, Vol. 3(2010):27-34 Copyright © 2009, Journal of Natural Products, INDIA, Dr. Sudhanshu Tiwari, All rights reserved 27 ISSN 0974 – 5211 Antibacterial and Phytochemical Evaluation of Three Medicinal Plants Akharaiyi Fred Coolborn* and Boboye Bolatito Microbiology Department, Federal University of Technology, P.M.B. 704, Akure, Ondo State, Nigeria * Corresponding author (Received 29 May 2009; Revised 04 June-11 July 2009; Accepted 08 August 2009) ABSTRACT The aqueos and ethanol extracts of the leaves, bark and roots of Senna hirsuta, Landolphia dulcis and Daniella oliveri were examined for possible sources of antimicrobial activities and phytochemical constituents. The preliminary evaluations of both the aqueous and ethanol extracts exhibited appreciable inhibitory activities on the tested pathogenic bacterial isolates at concentration of 20mg m/L. S.hirsuta showed more therapeutic activity where the aqueous extract of the leaves displayed inhibitory potency (30-37mm) in diameter on the tested bacterial isolates. The ethanol extract of the leaves showed inhibitory halo of between (30-38mm) in diameter. However, the leaves extracts of other plants as well demonstrated higher antibacterial potency than the bark and roots extracts. Saponins and alkaloids were recorded present in all the plants parts. While highest saponins constituent (5.10±0.11%) was recorded in the leaves extracts of L.dulcis, alkaloids was also highest in its leaves extract with a value of 2.98±0.12 %. The MIC of the extracts was similar in all the plants parts. The values ranged between 1.25-10mg/ ml. Keyword: Antibacterial; Medicinal plants. INTRODUCTION Plants have a limitless ability to synthesize aromatic substances mainly secondary metabolites, of which at least 12,000 have been isolated, a number estimated to be less than 10% of the total (Mallikharjuna, et al., 2007). The synthesized aromatic substances (Metabolites) are used by plants as defensive molecules against predation by microorganisms, insects and herbivores. However, some of which may involve in plant odour (terpenoides), pigmentation (tannins and quinines), and flavour (Capsacin) (Mallikharjuna, et al., 2007). However, these defensive molecules give plants their medicinal value which is appreciated by human beings because of their great importance in health care of individuals and communities. Journal of Natural Products Volume 3 (2010) www.JournalofNaturalProducts.com Research Paper

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