188宝金博页面版

  • 图案背景
  • 纯色背景
视图
标记
批注
批注本地保存成功，开通会员云端永久保存 去开通
hyysh

上传于：2015-11-18

粉丝量：117

该文档贡献者很忙，什么也没留下。


  • 相关
  • 目录
  • 笔记
  • 书签

188宝金博页面版:更多相关文档

  • The production of reactive oxygen species in peripheral blood neutrophils is modulated by airway mucous

    星级： 8 页

  • Reactive oxygen species generation by bovine blood neutrophils with different

    星级： 7 页

  • Reactive Oxygen Species Production in Peripheral Blood Neutrophils of Obstructive Sleep Apnea Patients

    星级： 6 页

  • Production of reactive oxygen species by photosystem II

    星级： 10 页

  • Reactive Oxygen Species

    星级： 52 页

  • Reactive Oxygen Species

    星级： 5 页

  • reactive oxygen species

    星级： 10 页

  • reactive oxygen species

    星级： 6 页

  • Reactive Oxygen Species

    星级： 11 页

  • Reactive Oxygen Species

    星级： 9 页

  • Role of GLUT1 in regulation of reactive oxygen species

    星级： 8 页

  • Roles of reactive oxygen species

    星级： 11 页

  • of cellular reactive oxygen species

    星级： 11 页

  • Reactive oxygen species regulation of immune function

    星级： 2 页

  • Reactive oxygen species in regulation of fungal development

    星级： 19 页

暂无目录

点击鼠标右键菜单,创建目录

    暂无笔记

    选择文本，点击鼠标右键菜单，添加笔记

    暂无书签

    在左侧文档中，点击鼠标右键，添加书签

    188宝金博页面版: Regulation of Reactive Oxygen Species Production by Peripheral Blood Neutrophils from Women with Postpartum Endometritis

    下载积分： 4990

    内容提示： 2050007-4888/05/1402?0205 ? 2005 Springer Science+Business Media, Inc.IMMUNOLOGY AND MICROBIOLOGYRegulation of Reactive Oxygen Species Productionby Peripheral Blood Neutrophils from Womenwith Postpartum EndometritisV. G. Safronova, N. K. Matveeva*, V. N. Mal’tseva,N. M. Kasabulatov*, N. V. Avkhacheva,L. V. Van’ko*, and G. T. Sukhikh*Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 140, No. 8, pp. 173-176, August, 2005Original article submitted December 23, 2004Production of rea...

    文档格式：PDF | 页数：4 | 浏览次数：910 | 上传日期：2015-11-18 09:09:40 | 文档星级：
    2050007-4888/05/1402?0205 © 2005 Springer Science+Business Media, Inc.IMMUNOLOGY AND MICROBIOLOGYRegulation of Reactive Oxygen Species Productionby Peripheral Blood Neutrophils from Womenwith Postpartum EndometritisV. G. Safronova, N. K. Matveeva*, V. N. Mal’tseva,N. M. Kasabulatov*, N. V. Avkhacheva,L. V. Van’ko*, and G. T. Sukhikh*Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 140, No. 8, pp. 173-176, August, 2005Original article submitted December 23, 2004Production of reactive oxygen species in unfractionated peripheral blood increased in partu-rient women without postpartum infectious complications and patients with postpartumendometritis. The control group included nonpregnant women with normal reproductivefunction. Intergroup differences were revealed in the degree of respiratory burst activationwith opsonized zymosan and response of isolated granulocytes to chemotactic peptide N-formyl-Met-Leu-Phen (1 µM). Production of reactive oxygen species tended to normal aftertherapy. We studied the effects of a specific mitogen-activated protein kinase p38MAPKinhibitor and inhibitors of tyrosine protein phosphatases and phosphatidylinositol-3-kinase.The role of p38MAPK in reactive oxygen species generation by cells changes significantlyin parturient women.Key Words: granulocyte; reactive oxygen species; intracellular signaling; postpartumendometritisInstitute of Cell Biophysics, Russian Academy of Sciences, Pushchino;*Research Center of Obstetrics, Gynecology, and Perinatology, RussianAcademy of Medical Sciences, Moscow. Address for correspondence:safronova@icb.psn.ru. V. G. SafronovaActivation of phagocytes is a key mechanism of in-flammation [4]. Polymorphonuclear neutrophilic gra-nulocytes (neutrophils) are most rapidly mobilizedduring the inflammatory response. The cytotoxic po-tential of these cells depends on the content of reactiveoxygen species (ROS). ROS generation by neutrophilsis determined by activity of the membrane enzymeNADPH oxidase, which is regulated by intracellularsignal systems [6]. They are considered as a target formedicinal drugs [8]. Various diseases are accompa-nied by changes in the intensity of ROS generation byneutrophils [11,13]. However, the mechanisms of re-gulation of NADPH oxidase activity remain unclear.It is important to study not only cells present in theinflammatory focus, but also those circulating in thevascular bed. This approach allows us to perform diag-nostics and monitoring of therapy with consideringcharacteristics of peripheral blood cells.The presence of neutrophils in the endometrialepithelium is considered as the major histological signof endometritis [5]. Previous studies revealed changesin functional activity of neutrophils and macrophagesin the cervical and endometrial fluid from patientswith endometritis and salpingoophoritis [3]. The pre-sence of neutrophils in the upper part of the repro-ductive tract is of considerable prognostic importancefor the diagnostics of infections [15]. Neutrophils wererevealed in the uterine fluid during endometritis [10].Increased content of bactericidal peptides from neutro-Bulletin of Experimental Biology and Medicine, Vol. 140, No. 2, August, 2005

    阅读了该文档的用户还阅读了这些文档

    188宝金博页面版:关于我们

    188宝金博页面版:帮助中心

    188宝金博页面版:关注我们

    • 新浪微博

    关注188宝金博页面版公众号

    188宝金博页面版
    阅读
    APP
    阅读
    返回
    顶部
    188宝金博页面版官网登录在线平台入口（2026已更新）—江苏协昌电子科技股份有限公司