Impact of asthma control on quality of life among palestinian childrenAli Aldirawi 1,6 , Ahmad R. Al-Qudimat 2 , Tamara Al Rawwad 3 , Fadwa Alhalaiqa 4 , Abdallah Alwawi 5? , Yan Jin 6 , Samer Abuzerr 7 , Eman Hammad 8 & Lina Rjoub 9Asthma is a chronic respiratory disease that signif i cantly af f ects children, impacting their health-related quality of life. This study aimed to explore the relationship between asthma control and quality of life among pediatric asthma patients in the West Bank, Palestine. A descriptive, cross-sectional study was conducted among 220 pediatric patients with asthma and their mothers, recruited from four governmental hospitals. Data were collected using self-administered questionnaires that included demographic information, an asthma control test, and the Pediatric Asthma Quality of Life questionnaire. The fi nal analysis included 182 children with a mean age of 8 years. The results showed that 71.9% of the children had uncontrolled asthma, with poor health-related quality of life reported by approximately 70% of this group. In contrast, only 2.7% of children with controlled asthma reported reduced quality of life. The fi ndings indicate a strong association between asthma control and health-related quality of life. Healthcare policies should prioritize educational programs for children and their parents to improve asthma management and overall well-being.Keywords Asthma control, Quality of life, Children, Asthma, PalestineAsthma is a prevalent chronic inf l ammatory condition that signif i cantly impacts the lives of pediatric patients, their families, and healthcare systems worldwide 1 . Af f ecting approximately 14% of children globally, asthma’s incidence and severity have escalated over the past three decades, as evidenced by rising hospitalization rates and asthma-related mortality 2 . Th is respiratory condition poses particular challenges for children, where its ef f ects on physical, social, and emotional well-being contribute to reduced quality of life (QoL) and increased healthcare needs 3 . Asthma prevalence among children in the Middle East varies considerably, with reports showing rates from 0.7% in Iran to 22.3% in Iraq. In Palestine, pediatric asthma prevalence dif f ers by location: 17.1% in villages, 8.8% in cities, and 9.4% in refugee camps, ref l ecting the inf l uence of socio-environmental factors 4 .Health-related quality of life (HRQoL), which considers the impact of health on functioning and well-being, is particularly relevant for children with asthma, as uncontrolled symptoms can hinder their physical, social, and emotional development. Asthma signif i cantly contributes to morbidity, reduced HRQoL, and increased healthcare costs. However, asthma detection and management remain suboptimal, particularly in low-income countries 5,6 . Guidelines emphasize adjusting treatment primarily based on asthma control, underscoring the need to understand the link between asthma management and HRQoL among pediatric patients in challenging settings 7 .Asthma impacts various aspects of children’s lives, potentially leading to depression, academic underachievement, behavioral issues, cognitive disorders, insomnia, and dif f i culties with internalizing and externalizing behaviors 8 . Social limitations, such as avoiding sleepovers and friends with pets, further restrict the lives of children with asthma 9–11 . Evaluating the impact of asthma control on HRQoL is vital for understanding disease burden, identifying risk factors, and informing public health strategies. Such assessments support strategic planning, informed resource allocation, and the evaluation of the ef f ectiveness of healthcare interventions 12 . 1 Xiangya School of Nursing, Central South University, Changsha, Hunan Province, China. 2 Department of Public Health, College of Health Sciences, Qatar University, Doha, Qatar. 3 Department of Social Work, School of Applied Humanities and Social Sciences, German Jordanian University, Amman, Jordan. 4 Pre-Clinical Af f airs, College of Nursing, Qatar University, Doha, Qatar. 5 Nursing Department, Faculty of Health Professions, Al-Quds University, Abu Dies, Palestine. 6 Nursing Department, Third Xiangya Hospital, Central South University, Changsha, China. 7 Department of Medical Sciences, University College of Science and Technology, Khan Younis, Gaza, Palestine. 8 Hebron Governmental Hospital, Al-Quds University, Abu Dies, Palestine. 9 Hebron Governmental Hospital, Hebron, Palestine. ? email: aalwawi@staf f .alquds.eduOPENScientif i c Reports | (2025) 15:7007 1 | https://doi.org/10.1038/s41598-025-91756-9www.nature.com/scientificreports